Mometamax in Dogs
gentamicin sulfate + mometasone furoate monohydrate + clotrimazole otic suspension
- Brand Names
- Mometamax
- Drug Class
- combination otic antibiotic, antifungal, and corticosteroid
- Common Uses
- otitis externa in dogs caused by susceptible bacteria and yeast, reducing ear canal inflammation, redness, and discomfort associated with ear infection, topical treatment for mixed bacterial and Malassezia ear infections when your vet confirms the eardrum is intact
- Prescription
- Yes — Requires vet prescription
- Cost Range
- $45–$110
- Used For
- dogs
Overview
Mometamax is a prescription ear medication used in dogs for otitis externa, which means inflammation and infection of the outer ear canal. It combines three active ingredients in one product: gentamicin, an antibiotic; clotrimazole, an antifungal; and mometasone, a steroid that helps reduce swelling, redness, itching, and pain. Your vet may choose it when ear cytology suggests a bacterial infection, a yeast infection, or both.
This medication is labeled for dogs and is usually given once daily for 7 days. It is not a general ear cleaner and it is not the right choice for every ear problem. Dogs with chronic or recurrent ear disease often need more than medication alone. Your vet may also recommend ear cleaning, recheck exams, or testing for underlying causes such as allergies, endocrine disease, ear mites, or middle ear disease.
One important safety point is that your vet should confirm the eardrum is intact before using Mometamax. Products that contain aminoglycosides such as gentamicin can carry a risk of ototoxicity if the eardrum is ruptured or if medication reaches the middle ear. That is why a proper ear exam matters before treatment starts.
For pet parents, the big takeaway is that Mometamax can be very helpful when it matches the infection present in the ear. It works best as part of a full plan, not as a stand-alone guess. If your dog keeps getting ear infections, ask your vet what is driving the recurrence so treatment can be matched to both the infection and the underlying cause.
How It Works
Mometamax works by combining three different actions in one ear medication. Gentamicin targets susceptible bacteria in the ear canal. Clotrimazole targets yeast, especially Malassezia pachydermatis, which is a common contributor to canine ear infections. Mometasone helps calm inflammation, which can reduce pain, swelling, discharge, and itching.
That combination matters because many dog ear infections are not caused by one problem alone. A dog may have inflamed skin from allergies, then develop secondary yeast or bacterial overgrowth. By addressing microbes and inflammation at the same time, Mometamax can help the ear canal become less swollen and more comfortable while the infection is being treated.
The medication is formulated as an otic suspension that stays in contact with the ear canal lining. After your vet or veterinary team confirms the ear is safe to treat, they may recommend cleaning the ear first so the medication can reach the affected tissue better. In some painful ears, cleaning may need to be gentle or delayed until inflammation starts to improve.
Even when Mometamax works well, it does not remove the reason the infection started. Dogs with allergies, moisture retention, narrow ear canals, excess hair, endocrine disease, or chronic skin disease may need a longer-term management plan. That is why follow-up with your vet is often part of successful care.
Side Effects
Many dogs tolerate Mometamax well when it is used as directed, but side effects can happen. Mild local effects may include temporary redness or discomfort at the application site. More serious reactions are uncommon but can include worsening ear pain, hearing changes, head tilt, circling, vomiting, diarrhea, reduced appetite, increased thirst, increased urination, skin thinning, or poor healing if the medication is used longer than directed.
Because Mometamax contains gentamicin, there is concern for ototoxicity if the eardrum is ruptured or if medication reaches deeper ear structures. Signs that need prompt veterinary attention include sudden hearing loss, head tilt, balance problems, or walking in circles. If any of these happen, stop the medication and contact your vet right away.
The steroid component, mometasone, can also matter in some dogs. Repeated or prolonged steroid exposure may increase the chance of steroid-related effects such as increased drinking and urination, delayed wound healing, or skin changes. This is one reason the labeled course is short and why your vet may want a recheck if the ear is not improving as expected.
See your vet immediately if your dog seems painful, neurologic, suddenly less responsive to sound, or worse after starting treatment. Ear disease can extend beyond the outer ear, and symptoms that look like a routine ear infection can sometimes point to middle ear involvement or another problem that needs a different plan.
Dosing & Administration
The labeled Mometamax dose depends on body weight and bottle size. For the 7.5 g, 15 g, and 30 g bottles, dogs under 30 pounds receive 4 drops in the affected ear once daily for 7 days, while dogs 30 pounds and over receive 8 drops once daily for 7 days. For the 215 g bottle, the labeled dose is 2 drops for dogs under 30 pounds and 4 drops for dogs 30 pounds and over, once daily for 7 days.
Your vet should examine the ear before treatment and confirm the eardrum is intact. In many cases, the ear should be cleaned and dried before medication is applied. Shake the bottle well, place the prescribed number of drops into the affected ear, and gently massage the base of the ear so the suspension spreads through the canal. Try to give it at the same time each day.
If you miss a dose, give it when you remember unless it is almost time for the next dose. Do not double the next dose. If your dog fights ear medication, ask your vet or veterinary nurse to show you a lower-stress technique. Good technique can make a big difference in whether the medication reaches the infected tissue.
Do not continue beyond the prescribed course unless your vet tells you to. If the ear still looks inflamed, smells bad, or seems painful after treatment, your dog may need repeat cytology, a culture, a different medication, or workup for an underlying cause. Recurrent ear infections are common in dogs with allergies and other chronic skin issues.
Drug Interactions
Mometamax is a topical ear medication, so whole-body drug interactions are usually less of a concern than with oral medications. Still, interactions and additive risks are possible. The most important one noted in veterinary guidance is concurrent use with other medications that contain gentamicin or related aminoglycosides, because that may increase the risk of ototoxicity.
The steroid component also matters. If your dog is already taking another corticosteroid, your vet may want to adjust the plan or monitor more closely for steroid-related effects such as increased thirst, increased urination, delayed healing, or skin changes. This is especially relevant in dogs with chronic skin disease, endocrine disease, or a history of repeated ear medication use.
Tell your vet about everything your dog receives, including prescription medications, over-the-counter products, supplements, medicated shampoos, and other ear products. Layering multiple ear medications without a clear plan can make the ear more irritated, dilute treatment, or make it harder to tell what is helping.
If your dog has recurring ear infections, ask whether cytology, culture, or imaging is needed before switching products. A different medication may be more appropriate if the infection pattern changes, resistant bacteria are suspected, or middle ear disease is part of the picture.
Cost & Alternatives
Spectrum of Care means you have options. Here are treatment tiers at different price points.
Conservative Care
- office exam
- basic ear exam and otoscopy
- ear cytology at many clinics
- home ear cleaner
- generic triple-combination otic medication when appropriate
- recheck if needed
Standard Care
- office exam
- otoscopic exam
- ear cytology
- professional ear cleaning if needed
- Mometamax or equivalent prescription
- follow-up visit or recheck cytology in some cases
Advanced Care
- comprehensive ear workup
- sedated ear flush or deep cleaning
- culture and susceptibility testing
- advanced medications or combination therapy
- imaging or referral in select cases
- management plan for underlying disease
Cost estimates as of 2026. Actual costs vary by location, clinic, and individual case.
Questions to Ask Your Vet
Bring these questions to your vet appointment to get the most out of your visit.
- Has my dog’s eardrum been checked and does it look intact? This helps confirm whether Mometamax is a safe option, since gentamicin-containing ear medications can be risky if the eardrum is ruptured.
- What did the ear cytology show: bacteria, yeast, or both? Knowing what is in the ear helps explain why this medication was chosen and whether it matches the infection present.
- Should I clean my dog’s ears before each dose, and if so, with what product? Some ears benefit from cleaning first, while others are too painful or inflamed and need a different approach.
- How many drops should I use in each ear, and for how many days? The labeled dose depends on body weight and bottle size, so clear instructions help avoid underdosing or overdosing.
- What side effects mean I should stop the medication and call right away? Prompt recognition of hearing changes, head tilt, worsening pain, or steroid-related effects can prevent more serious problems.
- If this infection comes back, what underlying cause should we investigate? Recurring ear infections often point to allergies, endocrine disease, anatomy issues, or chronic skin disease that also need attention.
- Would a generic equivalent or another ear medication be a reasonable option for my dog? This opens a conversation about treatment choices, home dosing preferences, and cost range without assuming one plan fits every family.
FAQ
What is Mometamax used for in dogs?
Mometamax is a prescription ear medication used to treat otitis externa in dogs caused by susceptible bacteria and yeast. It also helps reduce inflammation, redness, and discomfort in the ear canal.
Is Mometamax an antibiotic?
Partly. Mometamax is a combination medication. It contains gentamicin, which is an antibiotic, clotrimazole, which is an antifungal, and mometasone, which is a corticosteroid.
How often is Mometamax given?
The labeled schedule is once daily for 7 days, but the number of drops depends on your dog’s weight and the bottle size. Follow your vet’s instructions exactly.
Can I use Mometamax if my dog’s ear looks dirty?
Maybe, but do not guess. Many dogs need the ear cleaned before medication is applied, while others need a gentler plan. Your vet should examine the ear first and confirm the eardrum is intact.
What if my dog seems worse after starting Mometamax?
Stop the medication and contact your vet promptly if your dog has worsening pain, head tilt, walking in circles, sudden hearing changes, vomiting, or other concerning symptoms. These can signal irritation, ototoxicity, or a deeper ear problem.
Can I use leftover Mometamax from a previous ear infection?
It is best not to. Ear infections can be caused by different organisms at different times, and some dogs have a ruptured eardrum or middle ear disease that changes what is safe to use. Your vet should recheck the ear before restarting treatment.
Are there alternatives to Mometamax?
Yes. Depending on the ear cytology, your dog’s history, and how easy home treatment is, your vet may discuss generic equivalents, other prescription ear medications, in-clinic therapies, or a broader workup for recurrent disease.
Medical Disclaimer
The information provided on this page is for general informational and educational purposes only and is not intended as a substitute for professional veterinary advice, diagnosis, or treatment. Medications discussed on this page may be prescription-only and should never be administered without veterinary authorization. Never adjust dosages or discontinue medication without direct guidance from your veterinarian. Drug interactions and contraindications may exist that are not covered here. Always seek the guidance of a qualified, licensed veterinarian with any questions you may have regarding your pet’s medications or health. Use of this website does not create a veterinarian-client-patient relationship (VCPR) between you and SpectrumCare or any veterinary professional. If you believe your pet may be experiencing an adverse drug reaction or medical emergency, contact your veterinarian or local emergency animal hospital immediately.