Necrotic Stomatitis in Cows: Painful Mouth Infection and Feeding Problems

Quick Answer
  • Necrotic stomatitis in cows is a painful infection and tissue death in the mouth, often linked to bacteria entering through small wounds in the gums, tongue, or cheeks.
  • Common signs include drooling, foul breath, mouth pain, reluctance to eat, slow chewing, weight loss, and visible ulcers or gray-yellow dead tissue inside the mouth.
  • Young calves and stressed cattle are more likely to be affected, especially when rough feed, erupting teeth, oral trauma, or other mouth disease damages the lining of the mouth.
  • See your vet promptly if your cow is not eating, seems dehydrated, has fever, or has severe oral lesions. Mouth sores in cattle can also resemble reportable diseases, so a veterinary exam matters.
  • Typical 2025-2026 U.S. cost range for exam and treatment is about $150-$450 for mild field cases, $400-$1,200 for cases needing repeated treatment and supportive care, and $1,000-$2,500+ for severe or hospitalized cases.
Estimated cost: $150–$2,500

What Is Necrotic Stomatitis in Cows?

Necrotic stomatitis is a painful inflammatory disease of the mouth in which areas of the oral tissues become ulcerated and die. In cattle, this problem is often associated with secondary bacterial infection, especially when the lining of the mouth has already been damaged by rough feed, erupting teeth, foreign material, or another oral disease. A common bacterium involved in necrotic infections in cattle is Fusobacterium necrophorum, an anaerobic organism that normally lives in the body but can invade injured tissue.

Affected cows may have sores on the gums, cheeks, tongue, lips, or dental pad. These lesions can look raw, gray, yellow, or foul-smelling. Because the mouth is so painful, many cattle drool, chew slowly, drop feed, or stop eating enough. In calves, poor intake can quickly lead to dehydration and loss of condition.

Necrotic stomatitis is not a single look-alike condition. Your vet may also need to rule out other causes of oral lesions, including bovine papular stomatitis, vesicular stomatitis, trauma, chemical irritation, and other infectious diseases. That is one reason a prompt veterinary exam is important when a cow has mouth ulcers or sudden feeding problems.

Symptoms of Necrotic Stomatitis in Cows

  • Drooling or ropey saliva
  • Bad breath or foul odor from the mouth
  • Reluctance to eat, slow chewing, or dropping feed
  • Visible mouth ulcers, raw patches, or gray-yellow dead tissue
  • Pain when the mouth is touched or opened
  • Weight loss or poor growth in calves
  • Fever, depression, or reduced milk intake
  • Dehydration, sunken eyes, or weakness from not drinking
  • Swelling of the face or spread of infection into deeper tissues

Mild cases may start with drooling, bad breath, and slower eating. More serious cases can progress to obvious ulcers, fever, dehydration, and rapid loss of body condition. In calves, even a short period of poor nursing or poor feed intake can become significant.

See your vet immediately if your cow stops eating, cannot drink normally, has marked swelling, seems weak, or has widespread mouth lesions. Oral lesions in cattle can sometimes resemble reportable diseases such as vesicular stomatitis or foot-and-mouth disease look-alikes, so it is safest to have your vet assess the animal and advise on isolation and next steps.

What Causes Necrotic Stomatitis in Cows?

Necrotic stomatitis usually develops when the protective lining of the mouth is injured first and bacteria invade second. Rough stems, awns, sharp feed particles, wire, splinters, or other foreign material can create tiny wounds. Teething calves may also have irritated oral tissues that are easier for bacteria to invade. Once the tissue barrier is broken, bacteria such as Fusobacterium necrophorum can multiply in the low-oxygen environment of damaged tissue.

Other mouth diseases can set the stage as well. Viral or parapox lesions, chemical burns, and trauma may all leave the mouth vulnerable to secondary necrotic infection. Merck notes that F. necrophorum is a normal inhabitant of cattle and acts as an opportunistic pathogen in necrobacillosis, meaning it often takes advantage of preexisting tissue injury rather than causing disease in healthy tissue on its own.

Risk can increase with crowding, stress, poor nutrition, abrupt feed changes, and environments where cattle are exposed to coarse forage or contaminated feeding areas. Calves and young stock are often more vulnerable because they are still growing, may be under immune stress, and can decline quickly when mouth pain interferes with eating.

How Is Necrotic Stomatitis in Cows Diagnosed?

Your vet usually starts with a full history and careful oral exam. They will look for ulcers, dead tissue, odor, swelling, foreign material, and signs of dehydration or fever. In many cases, the appearance and location of the lesions, along with feeding difficulty and drooling, strongly suggest an oral infection with tissue necrosis.

Diagnosis also means ruling out other causes of mouth lesions. In cattle, that can include traumatic injury, bovine papular stomatitis, vesicular stomatitis, malignant catarrhal fever, bovine viral diarrhea-related oral disease, and other infectious or toxic causes. Because some oral diseases in cattle have regulatory importance, your vet may recommend isolation precautions until a more serious contagious disease is excluded.

If the case is severe, unusual, or not responding as expected, your vet may collect samples for cytology, culture, biopsy, or additional laboratory testing. They may also assess hydration status, body condition, and whether the infection appears limited to the mouth or has spread into deeper tissues. That information helps your vet match treatment intensity to the individual cow.

Treatment Options for Necrotic Stomatitis in Cows

Spectrum of Care means you have options. Here are treatment tiers at different price points.

Budget-Conscious Care

$150–$450
Best for: Mild to moderate cases that are still drinking, have localized lesions, and can be managed on-farm with close monitoring.
  • Farm-call or clinic exam
  • Basic oral exam and lesion assessment
  • Debridement or gentle cleaning if your vet feels it is appropriate
  • Systemic antibiotics selected by your vet for likely anaerobic infection
  • NSAID pain and inflammation control when appropriate
  • Soft, palatable feed and hydration support at home
  • Short-interval recheck if eating does not improve
Expected outcome: Often fair to good when lesions are caught early and the cow resumes eating within a few days.
Consider: Lower upfront cost range, but less intensive monitoring. Hidden foreign material, dehydration, or deeper infection may be missed without more diagnostics or repeat exams.

Advanced / Critical Care

$1,000–$2,500
Best for: Severe cases, calves that are weak or dehydrated, cattle with extensive tissue loss, or cases where the diagnosis is uncertain.
  • Hospitalization or intensive herd-health management
  • Sedated oral exam or advanced restraint for thorough evaluation
  • Aggressive fluid therapy and nutritional support
  • Repeated debridement, wound care, and close reassessment
  • Culture, biopsy, or additional diagnostics for severe, unusual, or nonresponsive lesions
  • Management of complications such as deep tissue spread, severe dehydration, or inability to eat
  • Isolation and regulatory guidance if a reportable disease cannot be ruled out immediately
Expected outcome: Variable. Some cattle recover well with intensive care, while advanced tissue destruction or delayed treatment can worsen outlook.
Consider: Most intensive option with the highest cost range and labor needs. It can provide the clearest diagnosis and strongest support for critical cases, but may not be necessary for every animal.

Cost estimates as of 2026-03. Actual costs vary by location, clinic, and individual case.

Questions to Ask Your Vet About Necrotic Stomatitis in Cows

Bring these questions to your vet appointment to get the most out of your visit.

  1. What do these mouth lesions most likely represent, and what other diseases need to be ruled out?
  2. Do you think this started from trauma, rough feed, a foreign body, or another infection?
  3. Does this cow need antibiotics, pain relief, fluids, or all three?
  4. Should this animal be isolated until contagious causes of oral lesions are excluded?
  5. What should I feed while the mouth is healing, and how do I know if intake is adequate?
  6. What signs would mean the infection is spreading or becoming an emergency?
  7. When should I expect improvement in drooling and eating after treatment starts?
  8. Are there herd-level changes I should make to reduce mouth injuries and future cases?

How to Prevent Necrotic Stomatitis in Cows

Prevention focuses on reducing mouth injury and lowering bacterial opportunity. Check hay, bedding, fencing, feeders, and pasture for sharp stems, awns, wire, splinters, and other objects that can cut the mouth. Feed management matters too. Abrupt changes to coarse or stemmy forage can increase oral irritation, especially in young cattle.

Good calf and herd management also helps. Keep feeding areas reasonably clean, reduce overcrowding, and support strong nutrition so cattle are better able to heal small oral injuries before they become infected. Watch teething calves and recently stressed animals closely, because they may be more likely to develop feeding problems after minor mouth trauma.

Prompt attention to early drooling, bad breath, or slow eating can prevent a small lesion from becoming a deeper necrotic infection. If one cow develops oral sores, ask your vet whether isolation or additional herd checks are appropriate. That is especially important when lesions are widespread, blister-like, or accompanied by other signs that could suggest a contagious disease rather than a simple traumatic mouth infection.