Ethmoid Hematoma in Donkeys: A Cause of Recurrent Nosebleeds

Quick Answer
  • Ethmoid hematoma is a blood-filled, locally destructive mass that forms near the ethmoid turbinates inside the nasal passages or sinuses.
  • The most common sign is intermittent, usually one-sided nosebleeding. Some donkeys also develop noisy breathing, reduced airflow, or a foul nasal odor if the mass is large.
  • Diagnosis usually requires a veterinary exam plus upper airway endoscopy, and many cases also need skull imaging to see how far the mass extends.
  • Treatment depends on size and location. Options may include repeated endoscopic injections, laser treatment, or surgery, with follow-up checks because recurrence is common.
  • See your vet promptly for repeated nosebleeds, and see your vet immediately if bleeding is heavy, breathing is difficult, or your donkey seems weak or distressed.
Estimated cost: $450–$6,500

What Is Ethmoid Hematoma in Donkeys?

Ethmoid hematoma, more precisely called progressive ethmoid hematoma, is a noncancerous but locally invasive mass that develops from the lining around the ethmoid turbinates in the back of the nasal cavity. Although most published veterinary information comes from horses, donkeys share very similar upper airway anatomy, so your vet will usually approach suspected cases in a comparable way.

These masses are made up of blood, fibrous tissue, and fragile surface lining. They can slowly enlarge over time and may extend into the nasal passages or nearby sinus compartments. That growth is why a donkey may seem fine between episodes, then have repeated nosebleeds over weeks or months.

A key point for pet parents is that this condition is not the same as a simple nose injury. Recurrent bleeding from one nostril, especially without obvious trauma, deserves a veterinary workup. Ethmoid hematomas can look dramatic, but the outlook varies widely depending on size, location, and whether the lesion comes back after treatment.

Symptoms of Ethmoid Hematoma in Donkeys

  • Intermittent bleeding from one nostril
  • Repeated small nosebleeds that stop and return over days to months
  • Reduced airflow through one nostril
  • Noisy breathing or snoring-type respiratory sounds
  • Blood-tinged nasal discharge
  • Foul-smelling breath or nasal odor
  • Visible mass on nasal endoscopy or, rarely, at the nostril if very large
  • Facial swelling or deformity in advanced sinus involvement
  • Heavy bleeding, weakness, or breathing distress

Small, occasional streaks of blood can still matter if they keep coming back. In equids, progressive ethmoid hematoma classically causes intermittent unilateral epistaxis, meaning repeated bleeding from one side of the nose. Larger lesions may also reduce airflow, create respiratory noise, or cause a bad odor.

See your vet immediately if the bleeding is heavy, both nostrils are involved, your donkey is breathing hard, seems pale or weak, or has any collapse, distress, or sudden facial swelling. Even mild but recurring nosebleeds deserve an appointment, because other causes such as sinus disease, trauma, fungal disease, clotting problems, or tumors can look similar at first.

What Causes Ethmoid Hematoma in Donkeys?

The exact cause of progressive ethmoid hematoma is still uncertain. Veterinary references describe it as a locally destructive, encapsulated vascular lesion of the nasal passages or paranasal sinuses. In plain language, that means it behaves like an expanding blood-rich mass, but it is not fully understood why it starts.

Researchers have proposed repeated small hemorrhages, abnormal blood vessel changes, and chronic local inflammation as possible contributors. What matters most clinically is that the lesion can continue to enlarge and bleed, even if the original trigger is never identified.

Because the cause is unclear, pet parents should avoid assuming a recurrent nosebleed is due to dry air, dust, or a minor bump. Those factors may irritate the nose, but they do not explain every case. Your vet may also need to rule out other causes of epistaxis, including sinus cysts, infection, dental-related sinus disease, trauma, fungal disease, foreign material, and less commonly neoplasia.

How Is Ethmoid Hematoma in Donkeys Diagnosed?

Diagnosis starts with a careful history and physical exam. Your vet will want to know whether the bleeding is one-sided or two-sided, how often it happens, whether there is exercise intolerance or noisy breathing, and whether there has been any trauma, dental disease, or weight loss.

The most useful first-line test is usually upper airway endoscopy. This allows your vet to look inside the nasal passages and see whether there is a characteristic discolored mass near the ethmoid region or blood tracking from that area. In horses, these lesions are often described as greenish-yellow to purple, and that appearance can strongly support the diagnosis.

Imaging is often the next step. Skull radiographs can help identify sinus involvement, but CT is often the most informative option when available because it shows the lesion's size, origin, and extension more clearly. Advanced imaging is especially helpful before treatment planning, since some lesions extend into areas where certain procedures carry more risk.

Your vet may also recommend bloodwork to assess blood loss or look for clotting problems, especially if the bleeding pattern is unusual. In some cases, biopsy is avoided or approached cautiously because these masses can bleed significantly, so diagnosis often relies on the combination of exam findings, endoscopy, and imaging.

Treatment Options for Ethmoid Hematoma in Donkeys

Spectrum of Care means you have options. Here are treatment tiers at different price points.

Budget-Conscious Care

$450–$1,400
Best for: Pet parents seeking budget-conscious, evidence-based options when bleeding is mild, the donkey is stable, and referral-level treatment is not immediately possible
  • Farm call or clinic exam
  • Sedated upper airway endoscopy
  • Basic bloodwork if bleeding has been recurrent
  • Skull radiographs when available
  • Monitoring plan with repeat rechecks
  • Referral discussion if the lesion appears large or sinus-based
Expected outcome: Short-term stabilization can be reasonable, but the mass usually does not resolve on its own. Ongoing or recurrent bleeding is likely without definitive treatment.
Consider: Lower upfront cost, but this approach may delay definitive care. It may miss deeper sinus extension, and repeated bleeding episodes can continue.

Advanced / Critical Care

$3,500–$6,500
Best for: Complex cases, large masses, lesions extending into the sinuses, recurrent cases, or pet parents wanting every available option
  • Referral hospital evaluation
  • CT or other advanced imaging for surgical planning
  • Laser ablation or sinus surgery for large, obstructive, or sinus-extending lesions
  • Hospitalization, intensive monitoring, and management of bleeding risk
  • Possible blood transfusion planning in cases with major hemorrhage risk
  • Post-procedure rechecks and repeat imaging or endoscopy if recurrence is suspected
Expected outcome: Outcome depends on lesion size, location, and whether the base can be fully treated. Advanced care can improve access to difficult lesions, but recurrence can still occur.
Consider: More intensive diagnostics and procedures can improve treatment planning, but cost range, travel, anesthesia or standing-surgery logistics, and follow-up needs are greater.

Cost estimates as of 2026-03. Actual costs vary by location, clinic, and individual case.

Questions to Ask Your Vet About Ethmoid Hematoma in Donkeys

Bring these questions to your vet appointment to get the most out of your visit.

  1. Does my donkey's bleeding pattern fit ethmoid hematoma, or are other causes more likely?
  2. Is the bleeding coming from one nostril only, and why does that matter?
  3. What did you see on endoscopy, and do you suspect the mass extends into the sinuses?
  4. Would skull radiographs be enough, or would CT change the treatment plan?
  5. Is this a case for monitoring, endoscopic treatment, or referral for surgery or laser therapy?
  6. How likely is recurrence in my donkey, and how often should we recheck after treatment?
  7. What signs at home mean I should call right away or seek emergency care?
  8. What is the expected cost range for the options available in my area, including follow-up visits?

How to Prevent Ethmoid Hematoma in Donkeys

There is no proven way to fully prevent progressive ethmoid hematoma, because the underlying cause is not well defined. That can feel frustrating, but it also means pet parents should focus on early detection rather than blame or second-guessing routine management.

The most practical step is to take any repeated nosebleed seriously, even if your donkey seems normal between episodes. Early evaluation may identify a smaller lesion before it causes more obstruction, sinus involvement, or repeated blood loss. Keeping notes on which nostril bleeds, how often it happens, and whether exercise seems to trigger it can help your vet.

Good general donkey care still matters. Regular dental care, prompt attention to nasal discharge or facial swelling, and a clean environment with reasonable dust control can support overall respiratory health and help your vet sort out other causes of epistaxis. These steps do not guarantee prevention, but they can make problems easier to catch and manage sooner.

If your donkey has already been treated for an ethmoid hematoma, follow-up is part of prevention too. Recurrence is common in equids, so scheduled rechecks with your vet are one of the best ways to catch regrowth before signs become severe again.