Exudative Epidermitis in Pigs: Signs, Treatment & Prevention

Quick Answer
  • Exudative epidermitis, often called greasy pig disease, is a bacterial skin infection in pigs most commonly caused by Staphylococcus hyicus.
  • It affects young piglets most often, especially suckling and recently weaned pigs, and can spread quickly after skin damage, mixing, crowding, or poor hygiene.
  • Common signs include red skin, greasy brown crusts around the eyes, nose, lips, and ears, depression, poor appetite, and painful foot lesions.
  • See your vet promptly if a piglet is not eating, seems weak, is getting dehydrated, or lesions are spreading fast. Severe cases can become life-threatening.
  • Typical U.S. veterinary cost range is about $150-$500 for an exam and basic treatment plan for a small group or pet pig, with higher costs if culture, susceptibility testing, fluids, or hospitalization are needed.
Estimated cost: $150–$500

What Is Exudative Epidermitis in Pigs?

Exudative epidermitis is a contagious bacterial skin disease of pigs, often called greasy pig disease. It is most commonly linked to Staphylococcus hyicus, a bacterium that can live on pigs without causing problems until the skin barrier is damaged. Once it gets into small abrasions, it can produce toxins that separate skin cells and lead to oozing, crusting, and the classic greasy appearance.

Young piglets are affected most often, especially suckling pigs and pigs around weaning. Older pigs usually develop more resistance with age, but they can still carry the bacteria and spread it to younger animals. In herd settings, outbreaks can move quickly when pigs are crowded, mixed, or housed on rough surfaces.

This condition is more than a cosmetic skin problem. Affected pigs can become painful, stop eating, lose fluids through damaged skin, and fall behind in growth. In severe cases, dehydration and weakness can become serious very fast, so early veterinary care matters.

Symptoms of Exudative Epidermitis in Pigs

  • Reddened skin, often starting around the eyes, nose, lips, or ears
  • Greasy, moist, or sticky skin with brown crusts or scabs
  • Skin thickening with spreading patches over the face, neck, belly, or body
  • Depression, listlessness, or separating from littermates
  • Reduced nursing or poor appetite
  • Foot or coronary band erosions, soreness, or reluctance to stand and walk
  • Dehydration, weakness, weight loss, or rapid decline
  • Rarely, hoof damage or sloughing in advanced cases

Early cases may look like mild facial irritation, but exudative epidermitis can worsen quickly in young piglets. The greasy coating is usually not very itchy, which can help distinguish it from some parasite problems. When lesions spread, pigs may stop eating, become weak, and lose fluids through damaged skin.

See your vet immediately if a piglet is weak, not nursing, dehydrated, or covered in rapidly spreading greasy crusts. Fast treatment is especially important in very young pigs and newly weaned groups.

What Causes Exudative Epidermitis in Pigs?

The main cause is infection with Staphylococcus hyicus. This bacterium usually needs a break in the skin to cause disease. Small abrasions from fighting, rough flooring, sharp edges, poor pen surfaces, or rubbing can give the bacteria a way in. New concrete and other abrasive housing materials are classic risk factors.

Several herd and piglet factors can make outbreaks more likely. These include crowding, earlier weaning, poor hygiene, high humidity, poor ventilation, and skin damage from parasites such as mange mites. Nutrition and immune status also matter. Piglets from gilts may be at higher risk because they may receive less protective immunity than piglets from older, previously exposed sows.

Carrier animals are important too. Older pigs, sows, and boars may carry the organism on the skin or in the reproductive tract without obvious disease. That means a healthy-looking herd can still expose vulnerable piglets, especially during birth, in the farrowing area, or after mixing at weaning.

How Is Exudative Epidermitis in Pigs Diagnosed?

Your vet will usually start with the pig's age, history, housing, and the appearance of the skin lesions. In many cases, exudative epidermitis is diagnosed presumptively from the clinical picture, especially when a young piglet has red skin that quickly becomes greasy and crusted around the face and feet.

If confirmation is needed, your vet may collect samples from skin lesions for bacterial culture and, when possible, antimicrobial susceptibility testing. This can be especially helpful in herd outbreaks, recurrent cases, or situations where treatment has not worked as expected. Resistance can occur, so culture can help guide a more targeted plan.

Your vet may also rule out other conditions that can look similar, including mange, lice, swine pox, parakeratosis, ringworm, and vesicular diseases. In severe or unusual cases, additional diagnostics may be recommended to assess dehydration, secondary infection, or broader herd health concerns.

Treatment Options for Exudative Epidermitis in Pigs

Spectrum of Care means you have options. Here are treatment tiers at different price points.

Budget-Conscious Care

$150–$300
Best for: Mild early cases, a small number of affected pigs, or pet pigs that are still eating and drinking and do not appear dehydrated.
  • Farm or clinic exam by your vet
  • Presumptive diagnosis based on age, lesions, and herd history
  • Isolation of affected pigs
  • Cleaning and drying the environment
  • Topical antiseptic skin care if your vet recommends it
  • Empiric medication plan based on likely bacteria and local patterns
Expected outcome: Often fair to good when started early, especially before lesions become widespread.
Consider: Lower upfront cost, but there is more uncertainty without culture. If resistance is present or the pig is sicker than expected, treatment may need to be changed.

Advanced / Critical Care

$700–$1,800
Best for: Severe cases, very young piglets, pigs that are weak or dehydrated, cases with rapid spread, or outbreaks causing deaths or major production losses.
  • Urgent veterinary reassessment or hospitalization
  • Injectable medications and intensive supportive care
  • Fluid therapy for dehydration
  • Culture, susceptibility testing, and broader herd diagnostics
  • Monitoring for weakness, poor intake, and secondary complications
  • Herd-level prevention planning, including review of flooring, stocking density, parasite control, and sow immunity
Expected outcome: Guarded to fair in advanced disease, but can improve with aggressive early support and correction of underlying herd factors.
Consider: Highest cost range and labor needs. It can be the right fit when a pig is crashing or when a herd outbreak needs a more precise, long-term control plan.

Cost estimates as of 2026-03. Actual costs vary by location, clinic, and individual case.

Questions to Ask Your Vet About Exudative Epidermitis in Pigs

Bring these questions to your vet appointment to get the most out of your visit.

  1. Does this look like exudative epidermitis, or could it be mange, lice, swine pox, or a nutrition problem?
  2. Does this pig need culture and susceptibility testing, or is a presumptive treatment plan reasonable?
  3. Is my pig dehydrated or painful, and what supportive care would help most right now?
  4. Should affected pigs be isolated, and for how long?
  5. Are there housing or flooring issues causing skin trauma in this pen or farrowing area?
  6. Should we check for mange mites or other parasites that may be damaging the skin?
  7. What signs would mean this has become an emergency?
  8. What prevention steps make the most sense for my herd or pet pig's environment?

How to Prevent Exudative Epidermitis in Pigs

Prevention focuses on protecting the skin barrier and lowering bacterial pressure. Start with the environment. Pens should be clean, dry, and well ventilated, with flooring and fixtures that do not scrape or cut the skin. Reducing crowding and avoiding unnecessary mixing can also lower fighting and skin trauma, especially around weaning.

Parasite control matters because mange and other skin irritants can create the openings that bacteria need. Good nutrition, steady access to water, and careful farrowing hygiene also help. In herd settings, thorough cleaning and disinfection between groups can reduce contamination in the environment.

Your vet may also talk with you about sow immunity, gilt management, and whether herd-level tools such as culture-guided treatment plans or autogenous vaccination are appropriate in recurring outbreaks. There is no single prevention plan that fits every farm or pet pig setup. The best approach depends on age group, housing, stocking density, and how often the problem returns.