Snuffles in Rabbits (Pasteurellosis): Symptoms & Treatment

Quick Answer
  • Snuffles is a common rabbit respiratory infection, often linked to Pasteurella multocida, but other bacteria can cause similar signs.
  • Common signs include sneezing, nasal discharge, matted fur on the front paws, watery eyes, reduced appetite, and noisy breathing.
  • See your vet immediately if your rabbit is open-mouth breathing, breathing hard, not eating, acting weak, or develops a head tilt.
  • Many rabbits improve with antibiotics and supportive care, but some develop chronic flare-ups and need long-term management.
  • Typical US cost range for diagnosis and treatment is about $120-$450 for mild outpatient care, $350-$900 with imaging and culture, and $800-$2,500+ for hospitalization or advanced procedures.
Estimated cost: $120–$2,500

What Is Snuffles in Rabbits (Pasteurellosis)?

Snuffles is the common name for an upper respiratory infection in rabbits. It is often associated with the bacterium Pasteurella multocida, but rabbits with similar signs may also have other bacteria involved, including Bordetella, Staphylococcus, or Pseudomonas. In some rabbits, the infection stays in the nose and eyes. In others, it can spread to the tear ducts, ears, lungs, skin, jaw, or even deeper tissues.

One reason snuffles can be confusing is that many rabbits can carry Pasteurella without looking sick. A positive culture does not always mean it is the only problem. Your vet has to interpret test results along with your rabbit's symptoms, exam findings, and response to treatment.

This condition matters because rabbits are obligate nasal breathers. That means a stuffy nose can become much more serious for a rabbit than it might for people. Even a mild-looking runny nose can lead to poor appetite, weight loss, stress, and dangerous breathing trouble if swelling and discharge build up.

Symptoms of Snuffles in Rabbits (Pasteurellosis)

  • Sneezing
  • Clear, white, or thick nasal discharge
  • Matted or dirty fur on the inside of the front paws
  • Watery or infected eyes
  • Noisy breathing or congestion
  • Reduced appetite or smaller droppings
  • Lethargy or weight loss
  • Head tilt, balance changes, or ear infection signs
  • Open-mouth breathing or obvious breathing effort

Mild snuffles may look like sneezing and a damp nose, but rabbits can worsen quickly. Be especially concerned if your rabbit stops eating, has fewer droppings, seems hunched, or sounds congested. See your vet the same day for breathing changes, thick discharge, or appetite loss. See your vet immediately for open-mouth breathing, blue-tinged gums, collapse, or a sudden head tilt.

What Causes Snuffles in Rabbits (Pasteurellosis)?

Snuffles is most commonly linked to Pasteurella multocida, a contagious bacterium that many rabbits are exposed to very early in life. Transmission can happen through close contact, respiratory droplets, and contact with contaminated secretions. Some rabbits carry the bacteria without symptoms and only become sick later when stress, crowding, poor ventilation, or another illness lowers their defenses.

Not every rabbit with a runny nose has pure pasteurellosis. Other bacteria can cause similar respiratory signs, and mixed infections are common. Dental disease can also mimic or worsen snuffles because overgrown tooth roots can affect the nasal passages and tear ducts. That is one reason your vet may recommend skull imaging if symptoms keep returning.

Risk tends to be higher in young rabbits, rabbits from crowded housing situations, and rabbits living in dusty, poorly ventilated, or ammonia-heavy environments. Stress from travel, bonding changes, surgery, or another illness can also trigger flare-ups in a rabbit that was previously stable.

How Is Snuffles in Rabbits (Pasteurellosis) Diagnosed?

Diagnosis starts with a hands-on exam by a rabbit-savvy veterinarian. Your vet will listen to the chest, check the nose and eyes, look for matted paws, assess hydration and body condition, and examine the teeth and jaw. Because rabbits can carry Pasteurella without illness, diagnosis is based on the whole picture, not one test result alone.

Depending on symptoms, your vet may recommend a deep nasal culture with sensitivity testing, cytology, skull or chest radiographs, and sometimes bloodwork. Culture and sensitivity can help guide antibiotic choices, especially in chronic or recurrent cases. Imaging is useful when your vet suspects pneumonia, ear involvement, abscesses, or dental disease contributing to the problem.

If your rabbit has a head tilt, eye discharge, or repeated relapses, your vet may also look for other conditions that can overlap with snuffles, including ear disease and dental root problems. In more complex cases, advanced imaging or referral to an exotics specialist may be the next step.

Treatment Options for Snuffles in Rabbits (Pasteurellosis)

Spectrum of Care means you have options. Here are treatment tiers at different price points.

Budget-Conscious Care

$120–$450
Best for: Stable rabbits with mild sneezing or discharge, normal breathing effort, and no signs of pneumonia or ear involvement.
  • Rabbit-focused exam
  • Basic assessment of breathing, hydration, appetite, and weight
  • Empiric oral antibiotic chosen by your vet when signs are mild and the rabbit is stable
  • Supportive care instructions for appetite support, hydration, and environmental cleanup
  • Follow-up recheck if symptoms are not improving
Expected outcome: Many mild cases improve, especially when treated early, but relapse is possible and some rabbits become chronic carriers with periodic flare-ups.
Consider: Lower upfront cost range, but there is less diagnostic detail. If the infection is resistant, mixed, or related to dental disease, symptoms may return and total costs can rise later.

Advanced / Critical Care

$800–$2,500
Best for: Rabbits with open-mouth breathing, pneumonia, severe congestion, head tilt, abscesses, major weight loss, or repeated failure of outpatient treatment.
  • Emergency or specialty evaluation
  • Hospitalization for oxygen support, warming, fluids, syringe feeding, and close monitoring
  • Advanced imaging or specialty procedures when severe dental disease, abscesses, sinus disease, or ear disease are suspected
  • Nebulization and intensive supportive care
  • Possible surgical procedures for abscesses, severe dental disease, or selected chronic nasal/sinus cases
Expected outcome: Guarded to fair, depending on how advanced the disease is and whether the lungs, ears, or deeper tissues are involved. Some rabbits stabilize well, while others need long-term management.
Consider: Most intensive and highest cost range. It can improve comfort and survival in severe cases, but chronic respiratory disease may still persist even after aggressive care.

Cost estimates as of 2026-03. Actual costs vary by location, clinic, and individual case.

Questions to Ask Your Vet About Snuffles in Rabbits (Pasteurellosis)

Bring these questions to your vet appointment to get the most out of your visit.

  1. Does my rabbit seem stable enough for outpatient care, or do you recommend hospitalization today?
  2. Based on the exam, do you think this is likely snuffles, dental disease, pneumonia, ear disease, or a combination?
  3. Would a culture and sensitivity change the treatment plan in my rabbit's case?
  4. Do you recommend skull or chest radiographs to look for tooth root disease or lung involvement?
  5. What signs mean the breathing problem is becoming an emergency at home?
  6. How should I support eating and hydration safely if my rabbit's appetite is down?
  7. Is my rabbit likely to have chronic flare-ups, and what follow-up schedule do you recommend?
  8. Should I separate this rabbit from other rabbits in the home, and for how long?

How to Prevent Snuffles in Rabbits (Pasteurellosis)

Prevention focuses on lowering stress and supporting healthy airways. Keep your rabbit's living space clean, dry, and well ventilated. Change bedding often, avoid dusty litter or hay storage areas, and reduce ammonia buildup from urine. Good nutrition matters too. A hay-based diet, fresh water, and regular veterinary care help support the immune system and overall respiratory health.

Because many rabbits can carry Pasteurella without obvious illness, prevention is not always about eliminating exposure. It is more about reducing the chance that a carrier becomes sick. Quarantine new rabbits before introductions, wash hands between handling rabbits with respiratory signs, and clean bowls, litter boxes, and shared surfaces regularly.

Routine checkups are also important because dental disease, chronic eye discharge, and subtle weight loss can be early clues that something deeper is going on. There is no routine pet rabbit vaccine for pasteurellosis in the United States. If your rabbit has had snuffles before, ask your vet what early warning signs should trigger a recheck so treatment can start before breathing and appetite worsen.